The PFP is more than two thirds of cases of viral origin, and therefore has been suggested that the early use of prednisone (steroid) and acyclovir (antiviral) would have some utility in the treatment of early-stage, marked by facial nerve inflammation.
On October 18, 2007 was published in the New England Journal of Medicine a double-blind study compared the effects of prednisone and acyclovir in Bell’s palsy or facial nerve palsy (PFP).
The study was conducted in Scotland led by Dr. Frank M. Sullivan, of the Scottish School of Primary Care at the University of Dundee, Scotland.
A 94.4% of patients receiving prednisone within 72 hours of the start of the PFP, had an excellent performance in following up to 9 months. 85.4% of those who received acyclovir had an excellent performance.Continue reading