Neurology Diagnostics

Posts Tagged ‘genetic’

A multicenter study is published today in JAMA has identified two genes that may be risk factors for development of Alzheimer’s disease late onset, although not help quantify the risk in carriers of these alterations.

Researchers at Boston University, U.S., in collaboration with scientists from the Rotterdam Study, coordinated by Monique Breteler, the Cardiovascular Health Study, led by Oscar Lopez, AGES-Reykjavik study, coordinated by Lenore Launer, the study in May AD , directed by Steve Younkin, the European Consortium of Alzheimer’s Disease, who leads Philippe Amouyel, the ACE Foundation in Barcelona, coordinated by Merce Boada, and the Consortium for Genetic and Environmental Risk of Alzheimer’s Disease, directed by Julie Williams, have identified two genes that may be risk factors for developing Alzheimer’s disease late onset.

The work, published today in The Journal of the American Medical Association, was carried out by analysis of genome wide association. The researchers have identified two new genes in specific locations in DNA. These genes appear to be independent of those already established by its association with the disease of Alzheimer’s, such as apolipoprotein E (APOE). Read the rest of this entry »