postheadericon The Role of Posterior Intralaminar Nuclei

posterior intralaminar nucleiRole of the posterior intralaminar nuclei of the thalamus in cognitive processes

The caudal intralaminar nuclei (ILP) of the thalamus are excellent candidates for the investigation of cognitive processes on the core area of psychobiology and clinical neuroscience due to its neuroanatomic and neurophysiological features, and its functional implications.

Are important components of the so-called brain activation systems, such as the ascending reticular activating system and the system of the basal ganglia-thalamic-cortical.

Although considered as functionally homogeneous, non-specific action, anatomical and functional relationships regular processes allow them to attention, learning and memory.

Experimental studies show that lesions of the parafascicular nucleus of rodents or centromedian parafascicular complex of primates to interfere with the processes of care and decrease the ability of learning and memory in different types of tasks.

The fact that there was a significant loss of neurons in the nuclei ILP in some pathologies with cognitive impairment, such as diencephalic amnesia, dementia, Parkinson’s and Alzheimer’s disease and disorders of the states of consciousness, seems also participation in cognitive processes mentioned.

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